Nonsecretory multiple myeloma

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چکیده

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"Nonsecretory" multiple myeloma.

Among 186 patients with multiple myeloma (MM), five women were diagnosed as having MM without M-component in serum and or urine at the diagnosis and along the evolution. Bone marrow plasmacytosis at greater than 30% was found in all patients and bone x-rays showed lytic lesions in all but one case, osteoporosis in all, and pathologic fractures in two. Serum electrophoresis showed a striking hyp...

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Cutaneous Plasmacytomas Secondary to Nonsecretory Multiple Myeloma

Introduction: Multiple myelomais characterized by neoplastic prolife ration of plasma cells in bone marrow. Cutaneous involvement occurs in only5 to 10% of patients and includes specific rare lesions such as multiple cutaneous plasmacytomas in advanced stages of disease. Case report: Male patient, 44years-old, diagnosed with nonsecretory multiple myeloma (Durie-Salmon stage III, International S...

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Nonsecretory Multiple Myeloma Presenting as an Intestinal Tumor

We report a case of a 43-year-old Caucasian man who presented with colicky abdominal pain and microcytic hypochromic anemia. The patient underwent a colonoscopy where a tumor was seen in the ascending colon; histology showed plasmacytoma of the colon. From the protein electrophoresis, no monoclonal band or free light chains were detected nor was urinary Bence Jones protein present. A bone marro...

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IgD (kappa) "nonsecretory" multiple myeloma: report of a case.

A case of IgD "nonsecretory" multiple myeloma in a 46-yr-old woman is reported. Despite the presence of disseminated osteolytic lesions, both serum protein electrophoresis and serum and urine immunoelectrophoresis were normal. In addition, bone scintigraphic study was normal. Bone marrow biopsy and aspirate obtained from the left femur lytic lesion showed only myelomatous proplasmocytes; when e...

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A Case of Nonsecretory Multiple Myeloma with Atypical Imaging Features

Multiple myeloma usually shows homogeneous enhancement on contrast-enhanced Magnetic Resonance imaging (MRI), and is accompanied by a monoclonal gammopathy in serum or urine. We report a case of nonsecretory myeloma, the diagnosis was difficult due to the absence of a monoclonal gammopathy and the presence of atypical imaging features.

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ژورنال

عنوان ژورنال: Indian Journal of Orthopaedics

سال: 2009

ISSN: 0019-5413

DOI: 10.4103/0019-5413.55979